Inventing advanced reagents and software for genomic analysis
from patented genome bioinformatic technologies:
Shannon pipeline software is used for high throughput interpretation of genomic variation:
- High accuracy prediction of functional non-coding variants. Currently available for splicing mutations. In the future, transcription factor binding site variants and mutations in untranslated regions.
- Genome scale performance, but hones in on a small number of functionally significant variants.
- Proven approach based on information theory.
- Rapid results.
- For use with CLC bio’s user-friendly Genomics Workbench and Server platforms
Single Copy (sc) technology: precise, sensitive, and informative genomic hybridization tools for genetic disease management.
- Fluorescent in-situ hybridization (scFISH) probes from our catalog or custom synthesized. scFISH probes offer the highest resolution available on the market.
- Low noise, genomic microarray designs for comparative genomic hybridization. Our genomic microarrays use sc technology to increase reproducibility and reduce cost per sample.
- Targeted solution capture arrays for hybridization enrichment with increased coverage for deep sequencing. Our solution capture arrays offer the highest genomic coverage available on the market for next generation sequencing.
Imaging chromosome abnormalities: Cytognomix has developed proprietary image analysis algorithms and software to automatically detect chromosome abnormalities found by light and fluorescence microscopy. Cytogenetic abnormalities are detected regardless of their appearance, shape or structure. An example is our software for detecting dicentric chromosomes in blood, which are diagnostic for ionizing radiation exposures.
E-mail: firstname.lastname@example.org Phone:519-661-4255 Fax:519-858-5142
Array CGH is commonly used to identify chromosome abnormalities by
genome-wide assessment of copy number. Systematic noise in microarray
data is diminished:
- More accurate and reproducible results from your products
- Higher quality data for regulatory filings
- Fewer probes required to call copy number genotypes-
- Potentially more samples per array— use of sectored arrays with lower per sample costs