Our online single copy FISH (scFISH) catalog:
A subscription to our MutationForecaster system provides genome browser access to our genome-wide custom probe designs through the cytogenetic Visual Analytics Decision Support Tool. This tool displays the locations of FISH and oligonucleotide products used in microarray design and hybridization enrichment for Next generation sequencing. If you don’t want to subscribe, you may also contact us to inquire about the probe catalog.
Discovery: Epigenetic differences in metaphase chromosomes detected by single copy fluorescence in situ hybridization (scFISH)!
Cytognomix is the exclusive provider of scFISH products to detect differential chromosome accessibility, as described in these recent peer-reviewed articles:
Hill, S.L., Rogan, P.K., Wang, Y.X. and Knoll, J.H. Differentially accessible, single copy sequences form contiguous domains along metaphase chromosomes that are conserved among multiple tissues. Molecular Cytogenetics, 14(1), 1-17, 2021. (pdf)
Khan W, Rogan PK*, Knoll JHM*. Localized, Non-random Differences in Chromatin Accessibility between Homologous Metaphase Chromosomes, Molecular Cytogenetics, 7: 70, 2014.
Khan W, Rogan PK*, Knoll JHM*. Reversing chromatin accessibility differences that distinguish homologous mitotic metaphase chromosomes. Molecular Cytogenetics 8: 65, 2015.
DNA Probes previously verified by FISH. Probes available for numerous congenital disorders, leukemia and other cancer abnormalities. Request one of our standard probes…(Bulk purchases only)