We have described and provide evidence for an explanation for how rapid onset, severe RNA viral infections, such as SARS-CoV-2 or Influenza, may develop:
Rogan PK, Mucaki EJ and Shirley BC. A proposed molecular mechanism for pathogenesis of severe RNA-viral pulmonary infections. F1000Research 2020, 9:943 (https://doi.org/10.12688/f1000research.25390.1)
There is an accompanying infographic describing the mechanism, which is cited in the article:
Finally, the paper cites this data archive that contains our genomic analyses and related software programs:
Zenodo: Characteristics of human and viral RNA binding sites and site clusters recognized by SRSF1 and RNPS1. http://doi.org/10.5281/