This week, listen to Wahab Khan present our latest discovery using ab initio scFISH at the 2013 meeting of the American Society of Human Genetics:
Title: Non-random, locus-specific differences in DNA accessibility are present in homologous metaphase chromosomes.(168) (10:00AM-10:15AM on Thursday October 24, location: Grand Ballroom CDE, Concourse Level, Westin Boston Waterfront Hotel) (Platform)
Author(s): W. A. Khan, P. K. Rogan, J. H. M. Knoll
Keywords: Cytogenetics, KW025 – chromosomal structure/function, KW062 – FISH, KW082 – genomic structure, KW088 – imprinting, KW162 – structure/function
These differences cannot be detected with conventional large target FISH probes or with labeled pools of oligos. Only Cytognomix`s ab initio scFISH probes are capable of visualizing differential accessibility in metaphase chromosomes.
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