Cytognomix offers many standard single copy probes previously validated by FISH  for research use. Probes have also been pre-designed covering most regions for customized production and validation for research applications. Probes have also been pre-designed covering most regions for customized production and validation for research applications. Genome-wide and targeted microarray designs available for array comparative genomic hybridization. Solution capture arrays are available for targeted sequence enrichment in deep sequencing applications.


Inventing advanced reagents and software for genomic analysis

from patented genome bioinformatic technologies:

Shannon pipeline software for high throughput interpretation of genomic variation:

  • High accuracy prediction of  functional non-coding variants.
  • Genome-scale performance; hones in on a small number of variants.
  • Proven approach based on information theory.
  • Rapid results (10 minutes/genome).
  • Now Available Online!

Introduction to this revolutionary product

Veridical software for RNASeq-based validation of predicted mutations:

  • First product on the market to validate mutations with NGS data
  • Statistical approach to confirm predictions from the Shannon pipeline
  • Validates thousands of predictions in a few hours
  • Peer-reviewed; see testimonials 


Single Copy (sc) technology: genomic hybridization products for genetic disease management:

Imaging chromosome abnormalities:

  • Patented image analysis algorithms and software to automatically detect chromosome abnormalities.
  • Cytogenetic abnormalities are detected regardless of chromosome appearance, shape or structure.
  • ADCI software for detecting dicentric chromosomes in blood, which are diagnostic for ionizing radiation exposures.
  • NIH funded

Contact us:

E-mail: or      Phone:519-661-4255

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Genome-scale interpretation of mutations with the Shannon pipeline.

Online subscriptions available.

manhattan-like plot

Software to predict splicing mutations along a chromosome








RNASeq validation of predicted mutations

Intron inclusion for the inactivating mutation (chr12:83359523 G>A) within TMTC2












NGS Hybridization Enrichment Pools for Complete Gene Sequencing

Breast cancer genes

Patented capture array content containing complete sequences of 7 breast cancer genes









Standard SC-FISH probes

catalog scFISH

DNA Probes previously verified by FISH research on congenital disorders, leukemia and other cancers.

Request probes


Automated Splice Site and Exon Definition Server

Annual subscriptions to the Automated Splice Site and Exon Definition Server
are available.
  • Highly cited, well validated
    • Recommended by the American College of Medical Genetics and Genomics
    • Designated as a medical device by the FDA
  • The most informative and accurate predictions of mRNA splicing mutations
  • Constitutive and  splicing regulatory protein binding sites
  • Priced competitively

Genomic microarrays

Array CGH is commonly used to identify chromosome abnormalities by
genome-wide assessment of  copy number. Cytognomix has:
  • Reduced noise in genomic microarray data
  • More accurate and reproducible results
  • Higher quality data for regulatory filings
  • Fewer probes required to call copy number genotypes
  • Use sectored arrays with lower per sample costs

Have us design your microarray


Customized SC-FISH probes

Access Cytognomix’s SC-Genome Browser

scFISH probes

Probes based on chromosome coordinate, gene, chromosomal band, and other characteristics. Manufactured on demand.

Contact us for browser access*

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