Subtelomeric SC-FISH probes Catalog

Probes to detect subtelomeric imbalances

These probes are closer to chromosome termini than competitor products. Click to see the Gallery of scFISH images

  Chr. Target   scFISH probes1  Competitor Recombinant probes2
Catalog Number Chr
Length(bp) Distance from Telomere (kb)3  Estimated clone size Approx distance of STS from telomere (kb)4
ST-0000101 1ptel 2531* 1,045.411 – 1,047.942 90 kb unknown
3930* 1,048.515 – 1,052.445
ST-0000102 1ptel
3512* 1,053.361 – 1,056.873
ST-0000103 1ptel
2671 3,858.025 - 3,860.694
ST-0000104 1ptel
1853 7,939.921 - 7,941.773 100 kb 236 ± 100
ST-0000105 1qtel
ST-0000106 1qtel 1632* 97.847 – 96.215
2503 89.194-86.692
ST-0000107 1qtel
2653 175 kb 322 ± 175
ST-0000108 2ptel 112.585 – 115.237
3355 2,398.933 - 2,402.287 60 kb 390 ± 46
ST-0000109 2qtel
ST-0000110 3ptel 2093* 181.265-183..325 80 kb 248 ± 80
1834* 199.161-200..994
ST-0000111 3ptel
2953 762.774 - 765.726 95 kb6 997 ± 95
ST-0000112 3qtel
2022*
ST-0000113 3qtel 595.753 – 593.731
ST-0000114 4ptel 1796 246.384 – 248.179; 417.863 – 419.7107 145 kb6 (220-292) ± 73
2426 442.967 - 445.387 130 kb 930 ± 130
ST-0000115 4qtel
ST-0000116 5ptel 2189 86.825 - 89.013 191kb unknown
2795 2,032.602 - 2,035.396 105 kb 227 ± 105
ST-0000117 5qtel
ST-0000118 5qtel 2661 2,019.454 - 2,022.114
ST-0000119 5qtel 2633* 627.290 – 624.657
ST-0000120  5qtel 1753* 422.516 – 420.763
ST-0000121 6ptel 2152 199.487 - 201.638 80 kb unknown
2554 175.551 - 178.104 100 kb (276-282) ± 94
ST-0000122 6qtel
ST-0000123 7ptel 2872 815.565 - 818.439 60 kb 218 ± 59
2434*
ST-0000124 7ptel 143.257 – 145.691
2348*
ST-0000125 7ptel 146.749 – 149.097
2574 1,095.575 - 1,098.148 95 kb 225 ± 95
ST-0000126 7qtel
1517*
ST-0000127 7qtel 28.945 – 27.428
1634*
ST-0000128 7qtel 5.405 – 3.771
1865*
ST-0000129 7qtel 81.313 – 79.448
ST-0000130 8ptel 2079 483.728 – 485.805 135 kb 1,200 ± 135

 

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1 scFISH probes developed from April 2003 genome draft are labeled with asterisk (*). The remaining probes were from April 01 draft except 1p (Nov 02), 2q, 3q, 4p, 5p, 6, 8q, 9p (June 02). Sequence IDs corresponding to these probes contain the UCSC database version number in the descriptions of these products.
2 Many of conventional FISH probes were developed by Knight et al. Am. J. Hum. Genet. 67: 320, 2000, and by Abbott Laboratories/Vysis, Inc.
3Distance from probe to end of the telomere reported in this table is based on the length of the interval from the probe boundary coordinates to the terminal nucleotide coordinates of each chromosome end in the April 03 version of genome sequence. The computer program BLAT at the Genome Browser website (genome.ucsc.edu) was used to determine these coordinates. Due to inaccuracy in the BLAT algorithm, the coordinates of probe boundaries may differ from the actual coordinates slightly.
4 The position of STS/ marker associated with the conventional FISH probe was determined in the April 03 version of the genome sequence. Often a single STS/ marker is identified on a clone. There is insufficient information available to determine the positions of STS markers on some of these clones. As a result, error in positioning a probe on the chromosome (ie. ± ) is generally the size of the clone provided in: American Journal of Human Genetics 67: p. 320, 2000, and by Abbott/Vysis, Inc . A standard deviation less than the estimated clone size indicates that more than one STS was localized to the clone.
6 Indicates clones with cross hybridizations to other chromosomes.
7 Probe recognizes a neighboring paralogous sequence in addition to the known interval.
8 Reported STS located on X chromosome only, but both commercial probes for sex chromosomes show homology with each other.
9 Probe detect four paralogs: three of which are on chromosome 9 and one which is on chromosome 2.
unknown = Reported STS/ markers could not be placed on genome sequence as they could not be located in all available genome databases or through communication with authors.
^hybridization was detected when probe was combined with other 10ptel probes labeled with “^”.
+ hybridization was detected when probe was combined with other 10ptel probes labeled with “+”.

 

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