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CYTOGNOMIX, Inc. |
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PERSONALIZED GENOMIC DIAGNOSTIC PRODUCTS |
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Cytognomix offers many standard single copy probes previously validated by FISH for research use. Probes have also been pre-designed covering most regions for customized production and validation for research applications. |
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DNA Probes previously verified by FISH. Probes available for numerous congenital disorders, leukemia and other cancer abnormalities. |
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Select probes based on chromosome coordinate, gene, chromosomal band, and other characteristics. Probes manufactured on demand (based on NCBI36/hg18). Red boxes represent different probes in this gene. |
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Standard and Custom Products for in situ hybridization (FISH)
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Improved genomic microarrays for array comparative genomic hybridization |
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Array CGH is commonly used to identify chromosome abnormalities by genome-wide assessment of sequence copy number. Fundamental questions remain about data quality, evident by inter-platform comparisons monitored by the US FDA. Coefficients of variation remain high between platforms. We have shown that noise in genomic hybridization is related to contaminating SC sequences present in repeat-enriched DNA used to block repetitive sequences. Systematic noise in microarray data can be significantly diminished with our ab initio single copy probe designs. For array designers, manufacturers, and researchers, this means: · More accurate and reproducible results from your products · Higher quality data for regulatory filings · Fewer probes required to call copy number genotypes- · Potentially more samples per array— use of sectored arrays with lower per sample costs Contact us to design your microarray. |
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Site map Cytognomix.com ® 15-March-2011 |
