{"id":4611,"date":"2019-02-15T04:50:47","date_gmt":"2019-02-15T04:50:47","guid":{"rendered":"http:\/\/www.cytognomix.com\/?p=4611"},"modified":"2019-02-15T04:50:47","modified_gmt":"2019-02-15T04:50:47","slug":"feb-14-2019-new-article-about-targeted-validation-of-mrna-splicing-mutations","status":"publish","type":"post","link":"https:\/\/www.cytognomix.com\/?p=4611","title":{"rendered":"Feb. 14, 2019. New article about targeted validation of mRNA splicing mutations"},"content":{"rendered":"<p>New article in bioRxiv:<br \/>\nExpression changes confirm predicted single nucleotide variants affecting mRNA splicing. E. J. Mucaki and P.K. Rogan. (<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/549089v1?fbclid=IwAR33enWKxRT3QjLGLjHbdZU21upJVeoGyS-ier49zh_9o06kYxu50kq_RW0\" target=\"_blank\" rel=\"noopener nofollow\" data-ft=\"{&quot;tn&quot;:&quot;-U&quot;}\" data-lynx-mode=\"asynclazy\" data-lynx-uri=\"https:\/\/l.facebook.com\/l.php?u=https%3A%2F%2Fwww.biorxiv.org%2Fcontent%2F10.1101%2F549089v1%3Ffbclid%3DIwAR33enWKxRT3QjLGLjHbdZU21upJVeoGyS-ier49zh_9o06kYxu50kq_RW0&amp;h=AT1wE2U0Dltr_XKqjR0hX3KJL3L-95_T78lsKyvHa3fVA1AmPPVk2s59gbvNVlaIiRXBlhLqLTsJsyJplbP75Pe1SCIKn5p-JoM6dcAf7BK-dhQBek23wa7COQrqaiH-_Dspx4ylMPFYr3_0PDXrpsONCCJr\">https:\/\/www.biorxiv.org\/content\/10.1101\/549089v1<\/a>)<\/p>\n<p>This paper describes high quality qRT-PCR and microarray expression data of predicted splicing variants. The results confirm results of genome-wide TCGA and ICGC RNASeq findings (<a href=\"https:\/\/f1000research.com\/articles\/7-1908\/v1?fbclid=IwAR2BcEqKJ4sFnLNFobXPGwyVQqbGwStbh6FkDfeZe8vqXgJ9c1tFieEeP4U\" target=\"_blank\" rel=\"noopener nofollow\" data-ft=\"{&quot;tn&quot;:&quot;-U&quot;}\" data-lynx-mode=\"asynclazy\" data-lynx-uri=\"https:\/\/l.facebook.com\/l.php?u=https%3A%2F%2Ff1000research.com%2Farticles%2F7-1908%2Fv1%3Ffbclid%3DIwAR2BcEqKJ4sFnLNFobXPGwyVQqbGwStbh6FkDfeZe8vqXgJ9c1tFieEeP4U&amp;h=AT3HTnrTukwamxrTEoLzRsSIAhNF8So028ZVTBmDkRlfN17vWLhbDtJb8snMJJnXHd7NmDCTc6f8QuteiYIBJ_MBDURtARsuuw_5hh0M1TmqUXuTbOskSnX937rrWSS-KS1F_zeQXR5AtBJJQtMH-prlQNby\">https:\/\/f1000research.com\/articles\/7-1908\/v1<\/a>). The genome scale results were obtained using CytoGnomix&#8217;s MutationForecaster (<a href=\"http:\/\/mutationforecaster.com\/?fbclid=IwAR2q1PZGnhmu0v6qYr0tl9ME5t9uEw0vX89CCkHWptzWiO69JIO6D6TQX2M\" target=\"_blank\" rel=\"noopener nofollow\" data-ft=\"{&quot;tn&quot;:&quot;-U&quot;}\" data-lynx-mode=\"asynclazy\" data-lynx-uri=\"https:\/\/l.facebook.com\/l.php?u=http%3A%2F%2Fmutationforecaster.com%2F%3Ffbclid%3DIwAR2q1PZGnhmu0v6qYr0tl9ME5t9uEw0vX89CCkHWptzWiO69JIO6D6TQX2M&amp;h=AT0m3TWV5WPlC_J14JNAeCPP2hh_CvJs2g3ear90tyqCztaejUZR1CHpqFqqT3bVg2gUjxSSq4nbJbTSAjcgU8fiyOpb_R7AHHm9hpeaoojZsWbsv4rub1RFmOKruxC56SIe0mRzP5FVkzg6poWpxSyphJHn\">http:\/\/mutationforecaster.com<\/a>\u00a0) system.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>New article in bioRxiv: Expression changes confirm predicted single nucleotide variants affecting mRNA splicing. E. J. Mucaki and P.K. Rogan. (https:\/\/www.biorxiv.org\/content\/10.1101\/549089v1) This paper describes high quality qRT-PCR and microarray expression data of predicted splicing variants. The results confirm results of genome-wide TCGA and ICGC RNASeq findings (https:\/\/f1000research.com\/articles\/7-1908\/v1). The genome scale results were obtained using CytoGnomix&#8217;s [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[],"_links":{"self":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/posts\/4611"}],"collection":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4611"}],"version-history":[{"count":1,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/posts\/4611\/revisions"}],"predecessor-version":[{"id":4612,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/posts\/4611\/revisions\/4612"}],"wp:attachment":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4611"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4611"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4611"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}