{"id":3877,"date":"2016-02-14T18:49:50","date_gmt":"2016-02-14T18:49:50","guid":{"rendered":"http:\/\/www.cytognomix.com\/?p=3877"},"modified":"2016-02-14T18:51:37","modified_gmt":"2016-02-14T18:51:37","slug":"feb-15-2016-improved-filtering-in-mutation-forecaster-in-variant-effect-predictor","status":"publish","type":"post","link":"https:\/\/www.cytognomix.com\/?p=3877","title":{"rendered":"Feb. 15, 2016.  Improved filtering  in Mutation Forecaster for Variant Effect Predictor"},"content":{"rendered":"<p>We have added new capabilities to Variant Effect Predictor. Exome sequencing reveals many variants that have little or no effect on phenotype. You can remove these variants in MutationForecaster with our new stringency filters. Different default levels of filtering are offered. These can also be customized based on allele frequencies, predicted SIFT, Polyphen, variant type (eg. synonymous change), or protein coding domain containing the variant.<\/p>\n<p><a href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2016\/02\/Capture.jpg\"><img loading=\"lazy\" class=\"alignleft  wp-image-3878\" alt=\"Capture\" src=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2016\/02\/Capture.jpg\" width=\"726\" height=\"345\" srcset=\"https:\/\/www.cytognomix.com\/wp-content\/uploads\/2016\/02\/Capture.jpg 1513w, https:\/\/www.cytognomix.com\/wp-content\/uploads\/2016\/02\/Capture-300x142.jpg 300w, https:\/\/www.cytognomix.com\/wp-content\/uploads\/2016\/02\/Capture-1024x485.jpg 1024w, https:\/\/www.cytognomix.com\/wp-content\/uploads\/2016\/02\/Capture-900x427.jpg 900w\" sizes=\"(max-width: 726px) 100vw, 726px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>We have added new capabilities to Variant Effect Predictor. Exome sequencing reveals many variants that have little or no effect on phenotype. You can remove these variants in MutationForecaster with our new stringency filters. Different default levels of filtering are offered. These can also be customized based on allele frequencies, predicted SIFT, Polyphen, variant type [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[],"_links":{"self":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/posts\/3877"}],"collection":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3877"}],"version-history":[{"count":5,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/posts\/3877\/revisions"}],"predecessor-version":[{"id":3883,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/posts\/3877\/revisions\/3883"}],"wp:attachment":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3877"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3877"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3877"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}