{"id":3674,"date":"2015-07-02T23:26:28","date_gmt":"2015-07-02T23:26:28","guid":{"rendered":"http:\/\/www.cytognomix.com\/?p=3674"},"modified":"2015-07-02T23:26:44","modified_gmt":"2015-07-02T23:26:44","slug":"july-3-2015-new-publication-on-breast-cancer-gene-mutation","status":"publish","type":"post","link":"https:\/\/www.cytognomix.com\/?p=3674","title":{"rendered":"July 3, 2015. New publication on breast cancer gene mutation"},"content":{"rendered":"<p><strong>FANCM c.5791C&gt;T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity, and is a familial breast cancer risk factor.<\/strong><br \/>\nP<a title=\"FANCM nonsense-splicing mutation\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26130695\" target=\"_blank\">eterlongo et al. Hum Mol Genet. 2015 Jun 30. pii: ddv251.<\/a><\/p>\n<div>\n<p>In this paper, we use information theory to demonstrate a new mechanism for disease mutations. It turns out that this a fairly common type of mutation in our unpublished studies of other data sources.<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>FANCM c.5791C&gt;T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity, and is a familial breast cancer risk factor. Peterlongo et al. Hum Mol Genet. 2015 Jun 30. pii: ddv251. In this paper, we use information theory to demonstrate a new mechanism for disease mutations. It turns out that this a fairly common type [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[],"_links":{"self":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/posts\/3674"}],"collection":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3674"}],"version-history":[{"count":2,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/posts\/3674\/revisions"}],"predecessor-version":[{"id":3676,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/posts\/3674\/revisions\/3676"}],"wp:attachment":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3674"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3674"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3674"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}