{"id":475,"date":"2011-05-09T15:17:58","date_gmt":"2011-05-09T15:17:58","guid":{"rendered":"http:\/\/localhost:14696\/?page_id=475"},"modified":"2025-12-01T22:41:16","modified_gmt":"2025-12-01T22:41:16","slug":"standard-and-custom-products-for-in-situ-hybridization-fish","status":"publish","type":"page","link":"https:\/\/www.cytognomix.com\/?page_id=475","title":{"rendered":"Single copy FISH"},"content":{"rendered":"

Our online single copy FISH (scFISH) catalog:\u00a0<\/em><\/h2>\n

A\u00a0subscription to our \u00a0MutationForecaster<\/a>\u00a0system provides genome browser access to our genome-wide custom probe designs through the \u00a0cytogenetic Visual Analytics Decision Support Tool. This tool displays the locations of\u00a0FISH and oligonucleotide products used in microarray design and hybridization enrichment for Next generation sequencing. \u00a0If you don’t want to subscribe, you may also contact us<\/a> to inquire about the probe catalog.<\/p>\n

\"new\"<\/a><\/h3>\n

Discovery: Epigenetic differences in metaphase chromosomes detected by single copy fluorescence in situ hybridization (scFISH)!<\/h3>\n

Cytognomix\u00a0<\/a>is the exclusive provider of scFISH products to detect\u00a0differential chromosome accessibility,<\/em>\u00a0as described in these recent peer-reviewed articles:<\/h4>\n

Hill, S.L., Rogan, P.K., Wang, Y.X. and Knoll, J.H. Differentially accessible, single copy sequences form contiguous domains along metaphase chromosomes that are conserved among multiple tissues. Molecular Cytogenetics<\/i>,\u00a014<\/i>(1), 1-17<\/a>, 2021. (pdf<\/a>)<\/strong><\/p>\n

Khan W, Rogan PK*, Knoll JHM*. Localized, Non-random Differences in Chromatin Accessibility between Homologous Metaphase Chromosomes, Molecular Cytogenetics,<\/em> 7<\/em>: 70<\/a>, 2014.\u00a0<\/strong><\/p>\n

Khan W, Rogan PK*, Knoll JHM*.\u00a0Reversing chromatin accessibility differences that distinguish homologous mitotic metaphase chromosomes. Molecular Cytogenetics 8<\/em>: 65<\/a>, 2015.<\/strong><\/p>\n

\n

Standard SC-FISH probes<\/a><\/h2>\n

\"\"<\/p>\n

DNA Probes previously verified by FISH.\u00a0Probes available for numerous congenital disorders, leukemia and other cancer abnormalities. \u00a0Request one of our standard probes<\/a>…(Bulk purchases only<\/em>)<\/p>\n

Customized SC-FISH probes<\/a><\/h2>\n

\"\"<\/p>\n

\n

Probes (red boxes) \u00a0manufactured upon request.\u00a0We have developed a genome-wide set of single copy probes. \u00a0\u00a0Request \u00a0custom\u00a0<\/span>pro<\/span><\/a>bes<\/a>\u00a0<\/span>for your particular genomic interval of interest<\/span>. (Bulk purchases only<\/em>)<\/span><\/p>\n<\/div>\n

\"patent\"<\/h3>\n
FISH probes, genomic microarrays and capture reagents for NGS are\u00a0based on our patented ab initio technology (US Patents\u00a07,734,424<\/a>, \u00a08,209,129, and\u00a08,407,013).<\/h6>\n
Our portfolio also includes other US and international patents covering scFISH probes (eg. US Patents 6,828,097, 7,014,997) , and pending patent applications.<\/h6>\n","protected":false},"excerpt":{"rendered":"

Our online single copy FISH (scFISH) catalog:\u00a0 A\u00a0subscription to our \u00a0MutationForecaster\u00a0system provides genome browser access to our genome-wide custom probe designs through the \u00a0cytogenetic Visual Analytics Decision Support Tool. This tool displays the locations of\u00a0FISH and oligonucleotide products used in microarray design and hybridization enrichment for Next generation sequencing. \u00a0If you don’t want to subscribe, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":[],"tags":[],"_links":{"self":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages\/475"}],"collection":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=475"}],"version-history":[{"count":30,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages\/475\/revisions"}],"predecessor-version":[{"id":5185,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages\/475\/revisions\/5185"}],"wp:attachment":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=475"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=475"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}