{"id":3538,"date":"2015-01-29T23:14:35","date_gmt":"2015-01-29T23:14:35","guid":{"rendered":"http:\/\/www.cytognomix.com\/?page_id=3538"},"modified":"2015-01-29T23:23:33","modified_gmt":"2015-01-29T23:23:33","slug":"cytognomix-user-variation-database-cuvd","status":"publish","type":"page","link":"https:\/\/www.cytognomix.com\/?page_id=3538","title":{"rendered":"Cytognomix User Variation Database (CUVD)"},"content":{"rendered":"<p>Developed from the widely-used Leiden Open Variation Database, CUVD stores and \u00a0manages the results of variant analysis by Automated splice site and exon definition analysis (ASSEDA), Shannon pipeline, Variant effect predictor (VEP), and Veridical. \u00a0It it editable and \u00a0is also capable of performing built-in realtime searches of other locus-specific databases, Clinvar, dbSNP, and the Exome Variant Server. \u00a0All samples can be searched for the same variant, or variants can be retrieved for individual samples.<\/p>\n<p>Below, we have imported results from \u00a0VEP from a breast tumor exome and searched other databases for a missence change in the <em>MIB2<\/em> gene:<\/p>\n<p><a style=\"line-height: 1.5em;\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2015\/01\/VEPBreastTumorexome-CUVD.jpg\"><img loading=\"lazy\" class=\"alignleft  wp-image-3539\" alt=\"VEPBreastTumorexome-CUVD\" src=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2015\/01\/VEPBreastTumorexome-CUVD.jpg\" width=\"926\" height=\"361\" srcset=\"https:\/\/www.cytognomix.com\/wp-content\/uploads\/2015\/01\/VEPBreastTumorexome-CUVD.jpg 1543w, https:\/\/www.cytognomix.com\/wp-content\/uploads\/2015\/01\/VEPBreastTumorexome-CUVD-300x116.jpg 300w, https:\/\/www.cytognomix.com\/wp-content\/uploads\/2015\/01\/VEPBreastTumorexome-CUVD-1024x398.jpg 1024w, https:\/\/www.cytognomix.com\/wp-content\/uploads\/2015\/01\/VEPBreastTumorexome-CUVD-900x350.jpg 900w\" sizes=\"(max-width: 926px) 100vw, 926px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><a href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2015\/01\/VEPbreasttumorexome-CUVDsearch.jpg\"><img loading=\"lazy\" class=\" wp-image-3540 aligncenter\" alt=\"VEPbreasttumorexome-CUVDsearch\" src=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2015\/01\/VEPbreasttumorexome-CUVDsearch.jpg\" width=\"679\" height=\"268\" srcset=\"https:\/\/www.cytognomix.com\/wp-content\/uploads\/2015\/01\/VEPbreasttumorexome-CUVDsearch.jpg 849w, https:\/\/www.cytognomix.com\/wp-content\/uploads\/2015\/01\/VEPbreasttumorexome-CUVDsearch-300x118.jpg 300w\" sizes=\"(max-width: 679px) 100vw, 679px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Developed from the widely-used Leiden Open Variation Database, CUVD stores and \u00a0manages the results of variant analysis by Automated splice site and exon definition analysis (ASSEDA), Shannon pipeline, Variant effect predictor (VEP), and Veridical. \u00a0It it editable and \u00a0is also capable of performing built-in realtime searches of other locus-specific databases, Clinvar, dbSNP, and the Exome [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"tags":[],"_links":{"self":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages\/3538"}],"collection":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3538"}],"version-history":[{"count":3,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages\/3538\/revisions"}],"predecessor-version":[{"id":3544,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages\/3538\/revisions\/3544"}],"wp:attachment":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3538"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3538"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}