{"id":2559,"date":"2012-10-20T02:38:10","date_gmt":"2012-10-20T02:38:10","guid":{"rendered":"http:\/\/www.cytognomix.com\/?page_id=2559"},"modified":"2025-12-01T22:40:22","modified_gmt":"2025-12-01T22:40:22","slug":"careers","status":"publish","type":"page","link":"https:\/\/www.cytognomix.com\/?page_id=2559","title":{"rendered":"Resources"},"content":{"rendered":"<h2>Links to the latest CytoGnomix products:<\/h2>\n<h3>Applications and consulting in Geostatistical Epidemiology<\/h3>\n<p style=\"padding-left: 40px;\"><strong>Monitoring and discriminating infectious disease hotspots from high disease burden regions, eg. for COVID-19:<\/strong><\/p>\n<p style=\"padding-left: 80px;\">Zenodo repository:\u00a0 <a href=\"http:\/\/doi.org\/10.5281\/zenodo.4032708\" class=\"broken_link\">Geostatistical Analysis of SARS-CoV-2 Positive Cases in the United States<\/a><\/p>\n<p style=\"padding-left: 80px;\">Defence Canada IDEaS project: <a href=\"https:\/\/www.canada.ca\/en\/department-national-defence\/programs\/defence-ideas\/signed-contribution-agreements.html\" class=\"broken_link\">Locating emerging COVID19 hotspots in Ontario after community transmission by time-correlated, geospatial analysis\u00a0<\/a><\/p>\n<p style=\"padding-left: 40px;\"><strong>Addressing large scale radiation incidents and accidents:\u00a0<\/strong><\/p>\n<p style=\"padding-left: 80px;\">Article in PLOS One: <a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0232008\">Meeting radiation dosimetry capacity requirements of population-scale exposures &#8230;<\/a>. (Funded by High performance computing consortium: <a href=\"https:\/\/www.soscip.org\/\">SOSCIP<\/a> and CytoGnomix)<\/p>\n<p style=\"padding-left: 80px;\">How to: <a href=\"http:\/\/dx.doi.org\/10.17504\/protocols.io.ba4nigve\">Protocol for Geostatistical Determination of Radiation Dosimetry Maps of Population-Scale Exposures\u00a0<\/a><\/p>\n<h3>Large scale Radiation Biodosimetry<\/h3>\n<p style=\"padding-left: 40px;\">Capacity of supercomputer version of Automated Dicentric Chromosome Identifier and Dose Estimator\u00a0 (ADCI) software: <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/718973v1\">Automated Cytogenetic Biodosimetry at Population-Scale <\/a>and <a href=\"https:\/\/www.mdpi.com\/journal\/radiation\" class=\"broken_link\">Radiation<\/a>, Radiation, 2021 (link to <a href=\"https:\/\/www.mdpi.com\/2673-592X\/1\/2\/8\" class=\"broken_link\">published article<\/a>).<\/p>\n<p style=\"padding-left: 40px;\">Scalable, democratized access to ADCI:<\/p>\n<p style=\"padding-left: 80px;\"><a href=\"https:\/\/adciwiki.cytognomix.com\/doku.php?id=adcionline:overview\">Overview of Cloud version- ADCI_Online<\/a><\/p>\n<p style=\"padding-left: 80px;\"><a href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2021\/03\/005_CAN.pdf\">Presentation to the International Atomic Energy Agency (CRP E35010)<\/a><\/p>\n<h3>Gene Expression Signatures for Radiation Biodosimetry<\/h3>\n<p style=\"padding-left: 40px;\">Mucaki, E.J., Shirley, B.C. and Rogan, P.K., 2021. Improved radiation expression profiling in blood by sequential application of sensitive and specific gene signatures.\u00a0<i>International Journal of Radiation Biology<\/i>, \u00a0\u00a0<a href=\"https:\/\/doi.org\/10.1080\/09553002.2021.1998709\" class=\"broken_link\">doi.org\/10.1080\/09553002.2021.1998709 \u00a0 \u00a0<\/a>Link to pdf: <a href=\"http:\/\/www.cytognomix.com\/?attachment_id=4964\" rel=\"attachment wp-att-4964\">Improved radiation expression profiling&#8230; <\/a><\/p>\n<p style=\"padding-left: 40px;\">Zhao, J.Z., Mucaki, E.J. and Rogan, P.K., 2018. Predicting ionizing radiation exposure using biochemically-inspired genomic machine learning.\u00a0<i>F1000Research<\/i>,\u00a0<i>7<\/i>(233), p.233.\u00a0 \u00a0Link to open access article: <a href=\"https:\/\/f1000research.com\/articles\/7-233\">https:\/\/f1000research.com\/articles\/7-233<\/a><\/p>\n<h3>Large Scale Repository of Cancer Splicing Mutations<\/h3>\n<p class=\"js-article-title\">Pan-cancer repository of validated natural and cryptic mRNA splicing mutations\u00a0 \u00a0(a major public resource of mRNA splicing mutations validated according to multiple lines of evidence of abnormal gene expression. )<\/p>\n<p style=\"padding-left: 40px;\">Article in F1000Research: <a href=\"https:\/\/f1000research.com\/articles\/7-1908\/v2\">Pan-Cancer repository of &#8230;..<\/a><\/p>\n<p style=\"padding-left: 70px;\">Presentation at the 2019 American College of Medical Genetics Annual Meeting:<\/p>\n<p style=\"padding-left: 100px;\"><a href=\"http:\/\/www.cytognomix.com\/?attachment_id=4620\" rel=\"attachment wp-att-4620\">Pan-cancer repository of validated natural and cryptic mRNA.ePoster<\/a><\/p>\n<h3>Interactive Website: <a href=\"http:\/\/chemotherapy.cytognomix.com\">Gene signatures for chemotherapy drug response<\/a><\/h3>\n<h3>Demo (Windows): <a style=\"font-size: 16px;\" href=\"https:\/\/radiation.cytognomix.com\">Automated Dicentric Chromosome Identifier and Dose Estimator\u00a0\u00a0<\/a><\/h3>\n<h3>Review on information theory-based splicing mutation analysis:<\/h3>\n<p style=\"padding-left: 30px;\"><a title=\"Interpretation of mRNA splicing mutations in genetic disease\" href=\"http:\/\/f1000research.com\/articles\/3-282\/v1\" target=\"_blank\" rel=\"noopener noreferrer\">Caminsky et al. 2014<\/a>, Videos describing this paper: <a title=\"short video about F1000 paper: nterpretation of mRNA splicing mutations in genetic disease:...\" href=\"https:\/\/youtu.be\/_IbFaPObcXI\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"broken_link\">short <\/a>and <a title=\"Long version of video on F1000Research article &quot;Interpreting genomic variants in rare and common diseases....&quot;\" href=\"https:\/\/youtu.be\/GRyHf_3PexU\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"broken_link\">long <\/a>versions.<\/p>\n<p><!--more--><\/p>\n<h3><a title=\"MutationForecaster\" href=\"http:\/\/mutationforecaster.com\" target=\"_blank\" rel=\"noopener noreferrer\">MutationForecaster system<\/a><\/h3>\n<address><a title=\"learn about MF\" href=\"https:\/\/mutationforecaster.com\/learn.php\" target=\"_blank\" rel=\"noopener noreferrer\">Learn more<\/a>&#8230;<\/address>\n<address>\u00a0<\/address>\n<h3><a href=\"http:\/\/splice.uwo.ca\" target=\"_blank\" rel=\"noopener noreferrer\">Automated Splice Site and Exon Definition Server<\/a><\/h3>\n<address>User manual (select link to open)<\/address>\n<address>Peer reviewed publications:<\/address>\n<address style=\"padding-left: 30px;\"><a title=\"Automated splice site and exon definition analysis paper 2013\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2013\/10\/Mucakietal2013all.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Mucaki et. al. 2013<\/a><\/address>\n<address style=\"padding-left: 30px;\"><a title=\"ASSA paper\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2013\/10\/NallaRogan2005.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Nalla Rogan \u00a02005<\/a><\/address>\n<address><a title=\"published articles citing ASSA and ASSEDA\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2013\/10\/Merged-ASSA-References-List.V5PKR-10-16-2013.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Literature citations<\/a><\/address>\n<address>Videos: \u00a0<a title=\"ASSEDA tutorial\" href=\"http:\/\/www.youtube.com\/watch?v=Qk-2PUd3kYQ\" target=\"_blank\" rel=\"noopener noreferrer\">YouTube Tutorial<\/a>, \u00a0 \u00a0<a title=\"Video abstract\" href=\"http:\/\/www.youtube.com\/watch?v=1T_G3ybT51k\" target=\"_blank\" rel=\"noopener noreferrer\">Wiley Video Abstracts<\/a><\/address>\n<address><a href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2014\/04\/BriefReviewOfMolecularInformationTheory-1.pdf\">Brief Review of Molecular Information Theory<\/a><\/address>\n<h2><!--more--><\/h2>\n<h3><a href=\"http:\/\/shannonpipeline.cytognomix.com\" target=\"_blank\" rel=\"noopener noreferrer\">Shannon Pipeline for mRNA Splicing Mutation Analysis<\/a><\/h3>\n<address><a title=\"Product sheet. Shannon splicing mutation pipeline V1.05\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2013\/10\/ProductsheetCytognomixShannonHumSplicingAug312012.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Product sheet<\/a><\/address>\n<address>Manual (Cytognomix Online Subscription): \u00a0<a href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2012\/10\/Shannon-mutation-analysis-documentation-webservice-3-10-2014.pdf\">Shannon mutation analysis documentation &#8211; webservice<\/a><\/address>\n<address><a title=\"Shannon pipeline user guide\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2013\/10\/ShannonPipelineInstructionManual_Version2_10_22_2013.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">User reference guide<\/a>\u00a0 (CLC Bio Genomics Workbench and Server)<\/address>\n<address><a title=\"trial server installation guide\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2013\/10\/TrialServerDocumentation.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Guide to installation of trial webserver<\/a>\u00a0<\/address>\n<address><a title=\"Brief introduction to individual information theory\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2013\/10\/White-paper.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">White paper<\/a>\u00a0describing capabilities and features<\/address>\n<address>Peer reviewed publications:<\/address>\n<address style=\"padding-left: 30px;\"><a title=\"Genomics Proteomics and Bioinformatics paper 2013\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2013\/04\/ShirleyetalGPB_11_77-85_2013wsupp.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Shirley et al. 2013<\/a><\/address>\n<address>Videos<\/address>\n<address style=\"padding-left: 30px;\"><a title=\"Intro to the Shannon pipeline\" href=\"http:\/\/www.clcbio.com\/files\/usermanuals\/shannon_pipeline_trial.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Stephanie Dorman and Ben Shirley<\/a> (hosted by CLC bio)<\/address>\n<address style=\"padding-left: 30px;\">2012:\u00a0<a title=\"Rogan and BioIT World\" href=\"http:\/\/www.youtube.com\/watch?v=xjdvzZXVTJ0#t=20\" target=\"_blank\" rel=\"noopener noreferrer\">BioIT World<\/a>, \u00a0\u00a0<a title=\"Tech Alliance presentation of Shannon pipeline\" href=\"http:\/\/www.youtube.com\/watch?v=3XcM1_3zOqw\" target=\"_blank\" rel=\"noopener noreferrer\">TechAlliance<\/a><\/address>\n<address>Presentations<\/address>\n<address style=\"padding-left: 30px;\">2012 American Society of Human Genetics meeting, <a title=\"CLC bio Medical Genomics Workshop presentation\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2013\/10\/Rogan_ashgCLCbiomedicalgenomicsworkshop2012.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">CLC bio Medical Genomics workshop<\/a><\/address>\n<address style=\"padding-left: 30px;\">2013: Slides from\u00a0<a href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2012\/10\/ShannonPipeline-OGI-Webinar-Present.pdf\">Shannon Pipeline Webinar 2013 &#8211; presentation<\/a><\/address>\n<h2><!--more--><\/h2>\n<h3>Veridical<\/h3>\n<address><strong>Validate predicted splicing mutations with RNASeq<\/strong><\/address>\n<address>Peer reviewed publications:<\/address>\n<address style=\"padding-left: 30px;\"><a href=\"http:\/\/f1000research.com\/articles\/3-8\/v2\" target=\"_blank\" rel=\"noopener noreferrer\">Viner et al. 2014<\/a><\/address>\n<address>Video<\/address>\n<address style=\"padding-left: 30px;\">2014: Coby Viner at <a href=\"http:\/\/www.cytognomix.com\/?post_type=duka&amp;p=3027\" target=\"_blank\" rel=\"noopener noreferrer\">Compute Ontario<\/a><\/address>\n<h2><!--more--><\/h2>\n<h3>Ab initio sc probes (FISH, NGS enrichment, genomic microarrays)<\/h3>\n<address>Peer reviewed publications:<\/address>\n<address><a href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2011\/05\/new.jpg\"><img loading=\"lazy\" class=\"alignleft wp-image-3545\" src=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2011\/05\/new.jpg\" alt=\"new\" width=\"49\" height=\"48\" srcset=\"https:\/\/www.cytognomix.com\/wp-content\/uploads\/2011\/05\/new.jpg 226w, https:\/\/www.cytognomix.com\/wp-content\/uploads\/2011\/05\/new-150x150.jpg 150w, https:\/\/www.cytognomix.com\/wp-content\/uploads\/2011\/05\/new-144x144.jpg 144w\" sizes=\"(max-width: 49px) 100vw, 49px\" \/><\/a><\/address>\n<address style=\"padding-left: 30px;\"><a title=\"Reversing chromatin differences...\" href=\"http:\/\/www.molecularcytogenetics.org\/content\/8\/1\/65\" target=\"_blank\" rel=\"noopener noreferrer\">Khan et al. 2015<\/a><\/address>\n<address style=\"padding-left: 30px;\">\u00a0<\/address>\n<address style=\"padding-left: 30px;\"><a title=\"Locus specific differences in accessibility with scFISH probes\" href=\"http:\/\/www.molecularcytogenetics.org\/content\/7\/1\/70\" target=\"_blank\" rel=\"noopener noreferrer\">Khan et al. 2014.<\/a><\/address>\n<address style=\"padding-left: 30px;\"><a title=\"Expanding probe repertoire and improviing reproducibility in genomic hybridization\" href=\"http:\/\/nar.oxfordjournals.org\/content\/41\/7\/e81\" target=\"_blank\" rel=\"noopener noreferrer\">Dorman et al. 2013<\/a><\/address>\n<address style=\"padding-left: 30px;\"><a title=\"Segmental duplication detection with scFISH\" href=\"http:\/\/www.molecularcytogenetics.org\/content\/4\/1\/15\" target=\"_blank\" rel=\"noopener noreferrer\">Khan et al. 2012<\/a><\/address>\n<address style=\"padding-left: 30px;\"><a title=\"Distortion by Cot-1 paper\" href=\"http:\/\/academic.cytognomix.com\/scFISH\/Newkirketal_NAR2005.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Newkirk et al. 2005<\/a><\/address>\n<address style=\"padding-left: 30px;\"><a title=\"Mora et al. 2005\" href=\"http:\/\/academic.cytognomix.com\/scFISH\/Mora_MolCellProb20_114.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Mora et al. 2005<\/a><\/address>\n<address style=\"padding-left: 30px;\"><a title=\"Knoll and Rogan 2003\" href=\"http:\/\/academic.cytognomix.com\/scFISH\/clinfishpaper.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Knoll and Rogan 2003<\/a><\/address>\n<address style=\"padding-left: 30px;\"><a title=\"Rogan et al. 2001\" href=\"http:\/\/academic.cytognomix.com\/scFISH\/genomeresearch11_1086.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Rogan et al. 2001<\/a><\/address>\n<address>Probe <a title=\"hybridization protocol\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2013\/10\/SC-FISH-probe-hybridization-protocol-Cytognomix.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">hybridization protocol<\/a> for scFISH<\/address>\n<address><a title=\"protocol for hybridization enrichment\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2013\/10\/Genomic-DNA-Capture-Array-and-Sequencing-Protocol_Cytognomix.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Hybridization enrichment<\/a>: \u00a0sequence capture protocol for Next Generation Sequencing library preparation<\/address>\n<h2><!--more--><\/h2>\n<h3>Cytogenetic Biodosimetry<\/h3>\n<address><a title=\"system for interpretation of dicentric chromosomes in radiation treated samples\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2012\/10\/AppNote_ChromosomeBiodosimetryForMassRadiationEmergencies_v21.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Application note<\/a><\/address>\n<address>Peer reviewed publications and patents:<\/address>\n<address style=\"padding-left: 30px;\"><a href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2012\/10\/Radiat-Prot-Dosimetry-2014-Rogan-rpd-ncu133.pdf\">Rogan et al. 2014<\/a><\/address>\n<address style=\"padding-left: 30px;\"><a title=\"Integrated Intensity Laplacian IEEE Transactions in Biomedical Engineering paper\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2013\/10\/TBME_subasingheetal2013.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Subasinghe et al. 2013<\/a><\/address>\n<address style=\"padding-left: 30px;\"><a title=\"High performance computing version of ADCI\" href=\"http:\/\/www.cytognomix.com\/wp-content\/uploads\/2013\/10\/ICIAFS_IEEEexplore.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Li et al. 2012<\/a><\/address>\n<address style=\"padding-left: 30px;\">Subasinghe et al. 2011<\/address>\n<address style=\"padding-left: 30px;\">Subasinghe et al. 2010<\/address>\n<address style=\"padding-left: 30px;\">US Patent\u00a08,605,981<b>\u00a0<\/b>and patents pending (PCT\/US11\/59257 ).<\/address>\n","protected":false},"excerpt":{"rendered":"<p>Links to the latest CytoGnomix products: Applications and consulting in Geostatistical Epidemiology Monitoring and discriminating infectious disease hotspots from high disease burden regions, eg. for COVID-19: Zenodo repository:\u00a0 Geostatistical Analysis of SARS-CoV-2 Positive Cases in the United States Defence Canada IDEaS project: Locating emerging COVID19 hotspots in Ontario after community transmission by time-correlated, geospatial analysis\u00a0 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3512,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"tags":[164,170,120,127,115,130,173,129,174,122,131,128,177,125,176,143],"_links":{"self":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages\/2559"}],"collection":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2559"}],"version-history":[{"count":80,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages\/2559\/revisions"}],"predecessor-version":[{"id":5174,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages\/2559\/revisions\/5174"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/media\/3512"}],"wp:attachment":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2559"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2559"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}