{"id":113,"date":"2011-03-17T19:22:30","date_gmt":"2011-03-17T19:22:30","guid":{"rendered":"http:\/\/localhost:14696\/?page_id=113"},"modified":"2025-11-27T20:10:51","modified_gmt":"2025-11-27T20:10:51","slug":"113-2","status":"publish","type":"page","link":"https:\/\/www.cytognomix.com\/?page_id=113","title":{"rendered":"Customized scFISH probes"},"content":{"rendered":"
\"\"

\"\" Snapshots of predesigned SC-FISH probes from selected regions of chromosomes 9 and 17<\/em><\/p><\/div>\n

Customized single copy FISH probes can detect small rearrangements in chromosomes with precision, without compromising sensitivity or specificity. Useful for chromosome breakpoint delineation or confirmation of subtle rearrangements suggested by other techniques.<\/p>\n

Features<\/h3>\n

Probes pre-designed for ~223,000 genomic intervals (average genomic resolution ~15 kb)
\nAvailable labeled or unlabeled
\nNo Cot-1 or blocking DNA required
\nProbes detect 100 fold smaller genomic targets than\u00a0 conventional FISH probes. Sizes range from 1.5 to 10 kb
\nOften multiple probes per gene available
\nProbes detect rearrangements in small genes
\nProbe validation by nested PCR or other rapid hybridization methods. Optional FISH validation available.
\nAll probes have been validated by FISH
\nResearch Use Only
\nCovered by\u00a0 US Pat. No 7,734,424<\/a>, \u00a0\u00a08,209,129<\/a>, and\u00a08,407,013<\/a><\/p>\n

MutationForecaster<\/h3>\n

A subscription to our \u00a0MutationForecaster<\/a>\u00a0system provides genome browser access to our genome-wide custom probe designs through the \u00a0cytogenetic Visual Analytics Decision Support Tool. This tool displays the locations of all of our custom FISH products. Or, contact us for the probes you are looking for.<\/p>\n

Automated Dicentric Chromosome Identifier and Dose Estimator<\/h3>\n

ADCI is available for Windows operating systems (with optional GPU acceleration) or through the internet via Amazon Webservices. See our wiki (link<\/a>).<\/p>\n","protected":false},"excerpt":{"rendered":"

Customized single copy FISH probes can detect small rearrangements in chromosomes with precision, without compromising sensitivity or specificity. Useful for chromosome breakpoint delineation or confirmation of subtle rearrangements suggested by other techniques. Features Probes pre-designed for ~223,000 genomic intervals (average genomic resolution ~15 kb) Available labeled or unlabeled No Cot-1 or blocking DNA required Probes […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":[],"tags":[46,53,25,29,63,64,48,49,66,67,69,70,51,72,36,22,23,21,19,103,169,41,42,43,44,92,93],"_links":{"self":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages\/113"}],"collection":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=113"}],"version-history":[{"count":6,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages\/113\/revisions"}],"predecessor-version":[{"id":5142,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=\/wp\/v2\/pages\/113\/revisions\/5142"}],"wp:attachment":[{"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=113"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cytognomix.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=113"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}