Aug. 13, 2018. Differential accessibility to homologous chromosomal loci confirmed by international consortium

A large international consortium based at Harvard University has demonstrated parental homolog-specific differences in chromatin accessibility on human chromosome 19:

Nir et al. BioRxiv  doi: 10.1101/374058 (Walking along chromosomes with super-resolution imaging, contact maps, and integrative modeling)

This work reproduces previous reports previously published  by CytoGnomix scientists using our patented scFISH™ probes:

Khan et al. Molecular Cytogenetics 2014 7:70  (Localized, non-random differences in chromatin accessibility between homologous metaphase chromosomes)

Khan et al.  Molecular Cytogenetics 2015 8:65 (Reversing chromatin accessibility differences that distinguish homologous mitotic metaphase chromosomes)

 

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